Primary hyperparathyroidism–associated pancreatitis: poor prognosis, distinct serum calcium trajectories, and proactive therapeutic implications

PHPT-AP is associated with a worse prognosis and requires proactive management. Serum calcium correlates with severity and should be monitored dynamically. Early surgery or continuous veno-venous hemofiltration may be warranted in severe cases. Prolonged PHPT with recurrent AP and lifestyle risk factors may contribute to CP.

Authors

Yabing Wang (ORCID: https://orcid.org/0000-0003-3539-2633)
Chengzhen Lyu (ORCID: https://orcid.org/0009-0002-9222-7327)
Zihan Yang (ORCID: https://orcid.org/0009-0003-7849-8830)
Fan Zf
Dong Wu (ORCID: https://orcid.org/0000-0002-4353-4518)
J N Li
Qingwei Jiang
Yonghao Chen

Institutions

Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Peking Union Medical College Hospital (CN)
Tibet Autonomous Region People's Hospital (CN)
Beijing Friendship Hospital (CN)

Publication Details

Journal: Gastroenterology report
Published: 2026-01-13
DOI: https://doi.org/10.1093/gastro/goag004
Primary Topic: Pancreatitis Pathology and Treatment
Type: article
Field-Weighted Citation Impact: 0.00

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article

Primary hyperparathyroidism–associated pancreatitis: poor prognosis, distinct serum calcium trajectories, and proactive therapeutic implications

Yabing Wang, Chengzhen Lyu, Zihan Yang, Fan Zf et al.

Jan 13, 2026

Gastroenterology report

Pancreatitis Pathology and Treatment

article

Primary hyperparathyroidism–associated pancreatitis: poor prognosis, distinct serum calcium trajectories, and proactive therapeutic implications

Yabing Wang, Chengzhen Lyu, Zihan Yang, Fan Zf, Dong Wu, J N Li, Qingwei Jiang, Yonghao Chen

January 13, 2026article en

Abstract

PHPT-AP is associated with a worse prognosis and requires proactive management. Serum calcium correlates with severity and should be monitored dynamically. Early surgery or continuous veno-venous hemofiltration may be warranted in severe cases. Prolonged PHPT with recurrent AP and lifestyle risk factors may contribute to CP.

Gastroenterology reportVol. 14

Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), Tibet Autonomous Region People's Hospital (CN), Beijing Friendship Hospital (CN)

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Openalex Percentile: Top 56%

Pancreatitis Pathology and Treatment

DOI Open Access PDF OpenAlex

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Primary hyperparathyroidism–associated pancreatitis: poor prognosis, distinct serum calcium trajectories, and proactive therapeutic implications — Yabing Wang, Chengzhen Lyu, et al. · Gastroenterology report (2026) | TGRS Research Map | TGRS