Clinical Features and Biomarkers Associated With Intensive Care–Dependent Refractory NMDAR Encephalitis
RI-NMDARE represents a distinct, high-risk subgroup with a severe clinical profile marked by rapid disease progression; the triad of seizures, movement disorders, and dysautonomia; and elevated biomarkers. RI-NMDARE is associated with poorer outcomes, underscoring the need for early recognition and tailored therapeutic strategies.
Authors
- Antonio Farina (ORCID: https://orcid.org/0000-0002-5551-0185)
- David Gonçalves (ORCID: https://orcid.org/0000-0002-7707-0918)
- Mélodie Aubart (ORCID: https://orcid.org/0000-0002-4383-7930)
- Marie Bénaiteau (ORCID: https://orcid.org/0009-0005-2347-6006)
- Géraldine Picard (ORCID: https://orcid.org/0000-0003-1282-267X)
- Le Duy (ORCID: https://orcid.org/0000-0001-7664-533X)
- Pauline Dumez
- Anthony Fourier (ORCID: https://orcid.org/0000-0002-3995-0500)
- Nicolás Lundahl Ciano-Petersen (ORCID: https://orcid.org/0000-0001-9555-4847)
- Macarena Villagrán‐García (ORCID: https://orcid.org/0000-0001-9236-2428)
- Élise Peter
- Cristina Bîrzu
- Bastien Joubert (ORCID: https://orcid.org/0000-0003-4631-3056)
- Iker Elosua-Bayes
- Jerome Honnorat
- Véronique Rogemond
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Universitat Autònoma de Barcelona (ES)
- Hôpital Necker-Enfants Malades (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Institut Necker Enfants Malades (FR)
- Centre de Recherche en Neurosciences de Lyon (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospices Civils de Lyon (FR)
- Hôpital Lyon Sud (FR)
- Pitié-Salpêtrière Hospital (FR)
- Vall d'Hebron Hospital Universitari (ES)
- Institut du Cerveau (FR)
- Instituto de Investigación Biomédica de Málaga (ES)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1212/nxi.0000000000200552
- Citations
- 2
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 78.30