Evaluation of Serum Levels of IL-17 and IL-22 in Leprosy: A Case-Control Study

Elevated serum IL-17 and IL-22 levels, particularly in borderline and reactional forms of leprosy, support a contributory role of the Th17/Th22 axis in disease immunopathogenesis and highlight their potential utility as biomarkers of inflammatory activity in lepra reactions.

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Publication Details

Journal
Cureus
Published
2026-02-13
DOI
https://doi.org/10.7759/cureus.103563
Primary Topic
Leprosy Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of Serum Levels of IL-17 and IL-22 in Leprosy: A Case-Control Study

Aditi Dabhra, Aneet Mahendra, Arushi Nanda (Gakhar), Sanjeev K. Gupta
Cureus
Leprosy Research and Treatment
article

Evaluation of Serum Levels of IL-17 and IL-22 in Leprosy: A Case-Control Study

Aditi Dabhra, Aneet Mahendra, Arushi Nanda (Gakhar), Sanjeev K. Gupta
article en

Abstract

Elevated serum IL-17 and IL-22 levels, particularly in borderline and reactional forms of leprosy, support a contributory role of the Th17/Th22 axis in disease immunopathogenesis and highlight their potential utility as biomarkers of inflammatory activity in lepra reactions.

CureusVol. 18(2)
Maharishi Markandeshwar University, Mullana (IN)
Good health and well-being
Openalex Percentile: Top 55%
Leprosy Research and Treatment
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Evaluation of Serum Levels of IL-17 and IL-22 in Leprosy: A Case-Control Study — Aditi Dabhra, Aneet Mahendra, et al. · Cureus (2026) | TGRS Research Map | TGRS