Peri-interventional antibiotic prophylaxis in endoscopic valve implantation for lung volume reduction in COPD patients: results from a German multicenter observational cohort

Peri-interventional antibiotic prophylaxis, whether single-dose or prolonged, did not improve clinical outcomes or reduce complication rates following ELVR. These findings indicate limited clinical benefit and support a more targeted, indication-based use of antibiotics in this setting.

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Publication Details

Journal
Infection
Published
2026-02-13
DOI
https://doi.org/10.1007/s15010-026-02742-w
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Peri-interventional antibiotic prophylaxis in endoscopic valve implantation for lung volume reduction in COPD patients: results from a German multicenter observational cohort

Stephan Eisenmann, Peter Schramm, Björn Schwick, Christian Grah et al.
Infection
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Peri-interventional antibiotic prophylaxis in endoscopic valve implantation for lung volume reduction in COPD patients: results from a German multicenter observational cohort

Stephan Eisenmann, Peter Schramm, Björn Schwick, Christian Grah, Nicolas Dickgreber, Angélique Holland, Thomas Sgarbossa, Urte Sommerwerck, Stephan Eggeling, S Kurz, Andreas Fertl, Carl Hünermann, Jacopo Saccomano, Dinah von Schöning, Hadis Darvishi, Leif Erik Sander, Stefan Andreas, Martin Witzenrath, Wolfgang Gesierich, on behalf of the German Lung Emphysema Registry study group, Christian Geltner, Joachim Hans Ficker, Kaid Darwiche, Eva Pappe, Bernd Schmidt, Ralf Eberhardt, Ralf-Harto Hübner
article en

Abstract

Peri-interventional antibiotic prophylaxis, whether single-dose or prolonged, did not improve clinical outcomes or reduce complication rates following ELVR. These findings indicate limited clinical benefit and support a more targeted, indication-based use of antibiotics in this setting.

Infection
München Klinik Bogenhausen (DE), Humboldt-Universität zu Berlin (DE), Vivantes Klinikum (DE), Krankenhaus der Augustinerinnen (DE), Forschungsinstitut Havelhöhe (DE), Paracelsus Medizinische Privatuniversität (DE), St. Raphael's Hospital (PK), Luisenhospital Aachen (DE), Asklepios Fachkliniken München-Gauting (DE), University Hospital Leipzig (DE), German Center for Lung Research (DE), DRK Kliniken Berlin (DE), Lungenklinik Hemer (DE), Klinik Donaustauf (DE), Stadtarchiv Ibbenbüren (DE), Martha-Maria Hospital (DE), Evangelische Lungenklinik Berlin (DE), University Hospital in Halle (DE), Asklepios Klinik Barmbek (DE)
European Respiratory Society
Good health and well-being
Openalex Percentile: Top 57%
Chronic Obstructive Pulmonary Disease (COPD) Research
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