Combined mesenchymal stem cells and telitacicept therapy for Evans syndrome refractory to various immunosuppressive: a case report

This case suggests that combined therapy with telitacicept and MSCs may represent an effective therapeutic option for patients with refractory ES. The complementary immunosuppressive mechanisms of BAFF/APRIL blockade and MSC-mediated immune regulation may provide synergistic disease control and warrant further investigation in larger clinical studies.

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Publication Details

Journal
Research and Practice in Thrombosis and Haemostasis
Published
2026-02-01
DOI
https://doi.org/10.1016/j.rpth.2026.103393
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Combined mesenchymal stem cells and telitacicept therapy for Evans syndrome refractory to various immunosuppressive: a case report

Huan Vinh Dong, Zhibo Han, Wei Liu, Lei Zhang et al.
Research and Practice in Thrombosis and Haemostasis
Immunodeficiency and Autoimmune Disorders
article

Combined mesenchymal stem cells and telitacicept therapy for Evans syndrome refractory to various immunosuppressive: a case report

Huan Vinh Dong, Zhibo Han, Wei Liu, Lei Zhang, Xiaolei Pei, Feng Xue, Renchi Yang
article en

Abstract

This case suggests that combined therapy with telitacicept and MSCs may represent an effective therapeutic option for patients with refractory ES. The complementary immunosuppressive mechanisms of BAFF/APRIL blockade and MSC-mediated immune regulation may provide synergistic disease control and warrant further investigation in larger clinical studies.

Research and Practice in Thrombosis and HaemostasisVol. 10(2)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Tianjin Institute of Pharmaceutical Research (China) (CN), Institute of Hematology & Blood Diseases Hospital (CN)
Zero hunger
Openalex Percentile: Top 55%
Immunodeficiency and Autoimmune Disorders
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