U-shaped prognostic signature: baseline platelet count and morphological parameters predict ovarian cancer outcomes in a 265-patient cohort

This study reveals a significant nonlinear association between platelet count and morphology and the risk of recurrence of ovarian cancer. Exploring the complex mechanisms linking baseline platelet characteristics to the prognosis of ovarian cancer will help facilitate the application of platelets as meaningful prognostic indicators and therapeutic targets in clinical practice.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-13
DOI
https://doi.org/10.3389/fonc.2026.1765566
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

U-shaped prognostic signature: baseline platelet count and morphological parameters predict ovarian cancer outcomes in a 265-patient cohort

Lin Zhu, Zhi Li, Yao Li, Qiushi Wang et al.
Frontiers in Oncology
Inflammatory Biomarkers in Disease Prognosis
article

U-shaped prognostic signature: baseline platelet count and morphological parameters predict ovarian cancer outcomes in a 265-patient cohort

Lin Zhu, Zhi Li, Yao Li, Qiushi Wang, Jie Li, Songning Wang, Cuiqin Sang
article en

Abstract

This study reveals a significant nonlinear association between platelet count and morphology and the risk of recurrence of ovarian cancer. Exploring the complex mechanisms linking baseline platelet characteristics to the prognosis of ovarian cancer will help facilitate the application of platelets as meaningful prognostic indicators and therapeutic targets in clinical practice.

Frontiers in OncologyVol. 16
Beijing Chao-Yang Hospital, Capital Medical University (CN), Beijing Chaoyang Emergency Medical Center (CN)
Good health and well-being
Openalex Percentile: Top 56%
Inflammatory Biomarkers in Disease Prognosis
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