Frailty and functional outcomes in patients with progressive fibrosing interstitial lung diseases receiving antifibrotic therapy: a real-life observational study
Frailty has been associated with poorer lung function and greater physical impairment in patients with fibrotic ILDs under antifibrotic treatment. Frail patients also more frequently require medication dose reduction due to adverse effects.
Authors
- Domenica Francesca Mariniello (ORCID: https://orcid.org/0000-0003-2932-3164)
- Carmine Picone (ORCID: https://orcid.org/0000-0002-5344-0056)
- Vito D’Agnano (ORCID: https://orcid.org/0000-0001-6742-9387)
- Stefano Sanduzzi Zamparelli (ORCID: https://orcid.org/0000-0003-3336-7290)
- Vasiliki Liakouli (ORCID: https://orcid.org/0000-0002-7392-9334)
- Alfonso Reginelli
- Gaetano REA
- Giulia Maria Stella
- Fabio Perrotta
- Andrea Bianco
Institutions
- University of Pavia (IT)
- Fatebenefratelli Hospital (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Ospedale Monaldi (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fmed.2026.1741725
- Citations
- 1
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 36.44