FTSJ1-mediated IL1RN mRNA instability promotes inflammation-driven hepatocellular carcinoma

High 2'-O-methyltransferase abundance predicts poor HCC prognosis. <i>FTSJ1</i> is a novel independent prognostic biomarker and oncogenic factor that promotes HCC progression by dysregulating the inflammatory response pathway, highlighting its translational potential in inflammation-driven HCC.

Authors

Shuya Jiang
Dongyang Ding
Jian Yu
Yunxi Zu
Yan Liao
Tengjiao Wang

Institutions

Second Military Medical University (CN)
Eastern Hepatobiliary Surgery Hospital (CN)

Publication Details

Journal: Journal of Gastrointestinal Oncology
Published: 2026-02-01
DOI: https://doi.org/10.21037/jgo-2025-693
Primary Topic: RNA modifications and cancer
Type: article
Field-Weighted Citation Impact: 0.00

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article

FTSJ1-mediated IL1RN mRNA instability promotes inflammation-driven hepatocellular carcinoma

Shuya Jiang, Dongyang Ding, Jian Yu, Yunxi Zu et al.

Feb 1, 2026

Journal of Gastrointestinal Oncology

RNA modifications and cancer

article

FTSJ1-mediated IL1RN mRNA instability promotes inflammation-driven hepatocellular carcinoma

Shuya Jiang, Dongyang Ding, Jian Yu, Yunxi Zu, Yan Liao, Tengjiao Wang

February 1, 2026article en

Abstract

Journal of Gastrointestinal OncologyVol. 17(1)

Second Military Medical University (CN), Eastern Hepatobiliary Surgery Hospital (CN)

Openalex Percentile: Top 57%

RNA modifications and cancer

DOI Open Access PDF OpenAlex

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