LAMP-coupled CRISPR-Cas12a assays: A promising new tool for molecular diagnosis of leishmaniasis
These new proof-of-concept LAMP-CRISPR assays, combining high sensitivity, multiple Leishmania species detection capability, and a portable lateral flow readout, hold promise as next-generation molecular tools to improve leishmaniasis diagnosis and surveillance, supporting One Health strategies for disease control.
Authors
- Luis Cabrera-Sosa (ORCID: https://orcid.org/0000-0002-8958-9709)
- Jose A. Nakamoto (ORCID: https://orcid.org/0000-0001-8312-433X)
- Percy Huaihua (ORCID: https://orcid.org/0000-0001-7981-6181)
- Eva Dueñas (ORCID: https://orcid.org/0000-0002-1468-367X)
- Ingrid Tirado
- Maria Manuel Cruz
- Jorge Arévalo
- Carlos M. Restrepo
- Vanessa Adaui
- Ariana Parra del Riego
Institutions
- Peruvian University of Applied Sciences (PE)
- National University of San Marcos (PE)
- Universidad Peruana Cayetano Heredia (PE)
- Universidad Andina del Cusco (PE)
- Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (PA)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1371/journal.pntd.0013456
- Citations
- 1
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 41.85