Pre-Neural Source of the Envelope-Following Response Revealed in Cases of Auditory Neuropathy
The EFR-H observations suggested a pre-neural origin, with the asymmetrical mechanoelectrical transduction process at the sensory hair cells as the main contributor. These findings provide further evidence of a pre-neural potential explaining the discrepancy between ABR and ASSR threshold estimations in ANSD. In addition, the results from the contralateral ears of unilateral ANSD cases may reveal subtle deficits typically undetected by standard audiological techniques. Overall, the study of noninvasive EFR recordings in ANSD may contribute to refining their diagnosis, ultimately improving their treatment.
Authors
- Antoine Nonclercq (ORCID: https://orcid.org/0000-0003-0292-9588)
- Federico Lucchetti (ORCID: https://orcid.org/0000-0001-9778-8460)
- Macarena Díaz (ORCID: https://orcid.org/0000-0002-6481-5589)
- Maxime Niesen (ORCID: https://orcid.org/0000-0002-0632-3463)
- Benoît Devroede
- Paul Deltenre
- Paul Avan
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Libre de Bruxelles (BE)
- Inserm (FR)
- Institut Pasteur (FR)
- Université Paris Cité (FR)
- Erasmus Hospital (BE)
- Assistance Publique – Hôpitaux de Paris (FR)
- Queen Fabiola Children's University Hospital (BE)
- University of Lausanne (CH)
Publication Details
- Journal
- Ear and Hearing
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1097/aud.0000000000001790
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00