Optimising Prescription of Treatment In older patients with Mild hypertension at Increased risk of Serious adverse Events (OPTIMISE2): protocol for a primary care based, open-label, randomised controlled non-inferiority trial
ISRCTN18030225. Registered on 19/09/2023. Secondary Identifying Numbers: University of Oxford Sponsor Protocol Number 16667. IRAS 1006598. CPMS 56390.
Authors
- Milensu Shanyinde (ORCID: https://orcid.org/0000-0003-4842-9247)
- Nicola Kenealy (ORCID: https://orcid.org/0000-0002-3113-0305)
- Margaret Ogden (ORCID: https://orcid.org/0000-0002-4611-5095)
- R F Payne
- David McCartney
- Marney Williams
- Andrew Clegg
- Joanna Moschandreas
- James P. Sheppard
- Simon de Lusignan
- Stavros Petrou
- Melanie Carr
- Jonathan Mant
- F. D. Richard Hobbs
- Ly-Mee Yu
- Richard J. McManus
Institutions
- University of Leeds (GB)
- University of Exeter (GB)
- University of Cambridge (GB)
- Oxford Health NHS Foundation Trust (GB)
- University of Oxford (GB)
Publication Details
- Journal
- Trials
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1186/s13063-026-09508-7
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00