A Nomogram Predictive Model for Drug-Resistant Tuberculosis Detection by GeneXpert MTB/RIF Assay in Paediatric Patients

In children and adolescents, TB is more common in older individuals and consists primarily of new cases. The nomogram model has good predictive value for DR-TB risk. Key predictors include retreatment, smoking, right middle lobe involvement and cavity formation. The GeneXpert MTB/RIF assay is a potential early screening tool for DR-TB. Further validation with larger samples is needed.

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Publication Details

Journal
Infection and Drug Resistance
Published
2026-02-01
DOI
https://doi.org/10.2147/idr.s542863
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00

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article

A Nomogram Predictive Model for Drug-Resistant Tuberculosis Detection by GeneXpert MTB/RIF Assay in Paediatric Patients

Lingchao Wang, Meigui Han, Jiwei Li, Shu Li et al.
Infection and Drug Resistance
Tuberculosis Research and Epidemiology
article

A Nomogram Predictive Model for Drug-Resistant Tuberculosis Detection by GeneXpert MTB/RIF Assay in Paediatric Patients

Lingchao Wang, Meigui Han, Jiwei Li, Shu Li, Can Guo, Na Wei, Dean Zhao, Fangmin Zhang, Weijie Guo, Nan Zhou, Xiaonan Guo
article en

Abstract

In children and adolescents, TB is more common in older individuals and consists primarily of new cases. The nomogram model has good predictive value for DR-TB risk. Key predictors include retreatment, smoking, right middle lobe involvement and cavity formation. The GeneXpert MTB/RIF assay is a potential early screening tool for DR-TB. Further validation with larger samples is needed.

Infection and Drug ResistanceVol. Volume 19
First Affiliated Hospital of Xinxiang Medical University (CN)
Xinxiang Medical University
Good health and well-being
Openalex Percentile: Top 56%
Tuberculosis Research and Epidemiology
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