A miniaturized mouse extracorporeal circulation model to characterize early hematologic and metabolic alterations

With stable core temperature and pH underscoring the system's controllability, this model provides a reproducible experimental platform for investigating the early molecular mechanisms of ECC-induced systemic responses and for supporting preclinical evaluation of potential therapeutic interventions in cardiovascular research.

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Publication Details

Journal
Frontiers in Physiology
Published
2026-02-13
DOI
https://doi.org/10.3389/fphys.2026.1740282
Primary Topic
Cardiac and Coronary Surgery Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

A miniaturized mouse extracorporeal circulation model to characterize early hematologic and metabolic alterations

Adili Abudourousuli, Qi Peng, Huifang Tang, Jiahao Guo et al.
Frontiers in Physiology
Cardiac and Coronary Surgery Techniques
article

A miniaturized mouse extracorporeal circulation model to characterize early hematologic and metabolic alterations

Adili Abudourousuli, Qi Peng, Huifang Tang, Jiahao Guo, Xiaohan Cheng, Ruishi Shen, Yijie Guo, Huashun Cui, Xiaoyu Wang, Yueyang Zhu, Xinzhi Pan
article en

Abstract

With stable core temperature and pH underscoring the system's controllability, this model provides a reproducible experimental platform for investigating the early molecular mechanisms of ECC-induced systemic responses and for supporting preclinical evaluation of potential therapeutic interventions in cardiovascular research.

Frontiers in PhysiologyVol. 17
Zhejiang Chinese Medical University (CN), Xinjiang Medical University (CN), Shanghai University of Traditional Chinese Medicine (CN), Shuguang Hospital (CN), Zhejiang University (CN)
National Natural Science Foundation of China, Zhejiang University
Good health and well-being
Openalex Percentile: Top 57%
Cardiac and Coronary Surgery Techniques
DOIOpen Access PDFOpenAlex
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A miniaturized mouse extracorporeal circulation model to characterize early hematologic and metabolic alterations — Adili Abudourousuli, Qi Peng, et al. · Frontiers in Physiology (2026) | TGRS Research Map | TGRS