Cancer and the risk of death, heart-failure hospitalization, and major adverse cardiovascular events in HFpEF: a propensity-matched cohort study
In middle-aged and older adults with HFpEF, concomitant cancer confers a sustained and clinically meaningful increase in mortality, HF hospitalization, and major cardiovascular events independent of traditional risk factors and biomarkers. These data support systematic cardio-oncology collaboration, biomarker-guided surveillance, and proactive HFpEF management in patients with cancer.
Authors
- Jianhua Jiao (ORCID: https://orcid.org/0000-0003-0227-7401)
- Chunling Li (ORCID: https://orcid.org/0000-0002-5633-7353)
- Fanhua Meng
- Yunbo Xie
- Peng Li
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Soochow University (CN)
- Beijing Geriatric Hospital (CN)
- Zhangjiakou Academy of Agricultural Sciences (CN)
- Zhangjiagang First People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fonc.2026.1728009
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health Commission of Hebei Province