Aging-related CD8 <sup>+</sup> T cell alterations and calcium/calmodulin dependent protein kinase 1D activation in the pathogenesis of diabetic kidney disease
Our results highlighted the important role of CD8<sup>+</sup> T cell in shaping the renal immune microenvironment in both DKD and aging. CAMK1D may serve as a shared molecular risk factor linking aging and diabetic renal injury.
Authors
- Yaping Zhou (ORCID: https://orcid.org/0000-0002-0659-1687)
- Weiming He (ORCID: https://orcid.org/0009-0007-2210-9452)
- Yining He
- Peiqi Zhu
- Ruijie Tang (ORCID: https://orcid.org/0009-0004-1905-4452)
- Ying Zhao
- Jing Zhao
- Zhengxin Liu
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-02-13
- DOI
- https://doi.org/10.7717/peerj.20762
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00