Physician Variation in Early Sepsis Management
In this mixed-methods study, ED physicians' antimicrobial administration time for sepsis varied significantly, but faster antimicrobial initiation practice patterns were not associated with overtreatment. Physicians with shorter door-to-antimicrobial times described a proactive, parallel processing approach to sepsis care.
Authors
- Joseph R. Bledsoe (ORCID: https://orcid.org/0000-0002-3005-2878)
- Ithan D. Peltan (ORCID: https://orcid.org/0000-0003-1730-234X)
- Chaorong Wu
- Angela P. Presson (ORCID: https://orcid.org/0000-0001-7400-3923)
- Matthew A. Christensen (ORCID: https://orcid.org/0000-0002-6021-8680)
- Fiona M. Schroeder
- Jorie Butler
- Tom H. Greene
- Catherine L. Hough
- Danielle Groat
- Samuel M. Brown
- Matthew H. Samore
- Blessing S. Ofori-Atta
- M. Blakely May
Institutions
- Intermountain Healthcare (US)
- Oregon Health & Science University (US)
- University of Utah (US)
- Intermountain Medical Center (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.56945
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Veterans Affairs
- Novartis
- Intermountain Research and Medical Foundation
- Regeneron Pharmaceuticals
- National Institutes of Health
- Centers for Disease Control and Prevention
- Agency for Healthcare Research and Quality
- University of California, San Francisco
- National Center for Advancing Translational Sciences