A systematic review and meta-analysis of blood-based biomarkers in anal squamous cell cancer treated with chemoradiotherapy
Hb and NLR show prognostic value for DFS in ASCC, while several other blood-based markers demonstrate consistent trends for OS. However, heterogeneity and small study numbers limit clinical application. These biomarkers are not yet as robust as clinicopathologic factors and prospective validation is required.
Authors
- Timothy J. Mitchell (ORCID: https://orcid.org/0000-0002-8309-5556)
- Colin William Steele (ORCID: https://orcid.org/0000-0001-8518-1223)
- Liam A Henderson
- Campbell SD Roxburgh
Institutions
- Beatson West of Scotland Cancer Centre (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- Critical Reviews in Oncology/Hematology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1016/j.critrevonc.2026.105215
- Primary Topic
- Colorectal and Anal Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00