Histological and clinical evaluation of novel deproteinized porcine bone mineral in socket preservation: a case report

Socket preservation, also known as alveolar ridge preservation, is a crucial dental procedure aiming to minimize the resorption of the alveolar ridge following tooth extraction. The use of bone substitutes has reduced the morbidity at the donor areas by decreasing the necessity of autogenous bone grafts and improved the patients' satisfaction and comfort. This case report aimed to evaluate the clinical and histological efficacy of deproteinized porcine bone mineral (DPBM) for socket preservation following molar extraction. A 48-year-old male patient underwent extraction of tooth #17 (maxillary left second molar), followed by socket preservation using DPBM. For comparative purposes, the patient's contralateral tooth #27 (maxillary right second molar) was extracted without socket preservation. After a 3-month follow-up, clinical evaluation revealed satisfactory dimensional stability of the alveolar ridge at the #17 site (bone height: 6.9 mm; bone width reduction: 7.4 mm), whereas the #27 site exhibited significant resorption (bone height: 6.4 mm; bone width: 6.9 mm). Histological analysis via Masson trichrome staining demonstrated new bone formation and tight integration between the DPBM particles and host bone at the #17 site. Subsequently, a dental implant was successfully placed at the preserved socket 4 months post-preservation, with stable osseointegration and functional restoration at the 1-year follow-up. This case confirms the effectiveness of DPBM in maintaining alveolar ridge dimensions and promoting new bone formation, providing a reliable foundation for subsequent implant therapy.

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Publication Details

Journal
Frontiers in Oral Health
Published
2026-02-13
DOI
https://doi.org/10.3389/froh.2026.1719449
Primary Topic
Dental Implant Techniques and Outcomes
Type
article
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article

Histological and clinical evaluation of novel deproteinized porcine bone mineral in socket preservation: a case report

Z Wang, Lina Xu, Jie Chen, Qing Wang
Frontiers in Oral Health
Dental Implant Techniques and Outcomes
article

Histological and clinical evaluation of novel deproteinized porcine bone mineral in socket preservation: a case report

Z Wang, Lina Xu, Jie Chen, Qing Wang
article en

Abstract

Socket preservation, also known as alveolar ridge preservation, is a crucial dental procedure aiming to minimize the resorption of the alveolar ridge following tooth extraction. The use of bone substitutes has reduced the morbidity at the donor areas by decreasing the necessity of autogenous bone grafts and improved the patients' satisfaction and comfort. This case report aimed to evaluate the clinical and histological efficacy of deproteinized porcine bone mineral (DPBM) for socket preservation following molar extraction. A 48-year-old male patient underwent extraction of tooth #17 (maxillary left second molar), followed by socket preservation using DPBM. For comparative purposes, the patient's contralateral tooth #27 (maxillary right second molar) was extracted without socket preservation. After a 3-month follow-up, clinical evaluation revealed satisfactory dimensional stability of the alveolar ridge at the #17 site (bone height: 6.9 mm; bone width reduction: 7.4 mm), whereas the #27 site exhibited significant resorption (bone height: 6.4 mm; bone width: 6.9 mm). Histological analysis via Masson trichrome staining demonstrated new bone formation and tight integration between the DPBM particles and host bone at the #17 site. Subsequently, a dental implant was successfully placed at the preserved socket 4 months post-preservation, with stable osseointegration and functional restoration at the 1-year follow-up. This case confirms the effectiveness of DPBM in maintaining alveolar ridge dimensions and promoting new bone formation, providing a reliable foundation for subsequent implant therapy.

Frontiers in Oral HealthVol. 7
Fudan University (CN), Shanghai Ninth People's Hospital (CN), Zhongshan Hospital (CN), Stomatology Hospital (CN)
Life in Land
Openalex Percentile: Top 57%
Dental Implant Techniques and Outcomes
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