Histological and Inflammatory Changes in Thyroid Glands and Early Growth Outcomes in Offspring of Rats Exposed to Ambient Air Pollution near a Petrochemical Complex: A Preliminary Study
The results indicate that proximity of rats to the CPC was a determining factor in the development of histological abnormalities and increases in inflammatory cytokine markers in the thyroid glands of the offspring. In addition, the offspring born near the CPC had lower birth weights and shorter craniocaudal lengths compared to the animals in the control group.
Authors
- Rodrigo P. de Carvalho
- Maria Angela Zaccarelli-Marino (ORCID: https://orcid.org/0000-0003-1448-7609)
- Nuha Ahmad Dsouki (ORCID: https://orcid.org/0000-0001-5882-1600)
- Juliana Mora Veridiano (ORCID: https://orcid.org/0000-0002-5096-7098)
- Mônica Akemi Sato (ORCID: https://orcid.org/0000-0001-8627-363X)
Institutions
- Morpho (United States) (US)
- Faculdade de Medicina do ABC (BR)
- Associação Paulista de Medicina (BR)
- Fundação do ABC (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Life
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3390/life16020329
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00