CPNE3 promotes colorectal cancer progression by regulating KIF4-mediated autophagy
CPNE3 promotes CRC progression by interacting with KIF4 and regulating PI3K/AKT/mTOR and autophagy pathways. The CPNE3-KIF4 axis is a potential therapeutic target.
Authors
- Wu Yongyou
- Chong Tang (ORCID: https://orcid.org/0000-0001-6675-8664)
- Yasu Jiang
- Wu Teng
Institutions
- Xuzhou Medical College (CN)
- Nantong University (CN)
- Soochow University (CN)
- Second People's Hospital of NanTong (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Second People’s Hospital of Huai’an (CN)
Publication Details
- Journal
- Journal of Gastrointestinal Oncology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.21037/jgo-2025-735
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Massachusetts Department of Agricultural Resources
- Science and Technology Project of Nantong City