Maternal migraine and offspring ADHD: triangulating the evidence
Our findings do not support a direct intrauterine causal effect of maternal migraine on offspring ADHD traits. Instead, the observed associations might reflect shared genetic overlap between migraine and ADHD. Future studies should characterize the shared genetic architecture underlying migraine-ADHD links, distinguishing pleiotropic effects from mediated pathways.
Authors
- Yaxin Luo
- Christina Dardani (ORCID: https://orcid.org/0000-0002-2019-7897)
- Robyn E. Wootton (ORCID: https://orcid.org/0000-0003-3961-3202)
- Apostolos Gkatzionis (ORCID: https://orcid.org/0000-0003-4942-0025)
- Evie Stergiakouli
Institutions
- Norwegian Institute of Public Health (NO)
- Bristol City Council (GB)
- University of Bristol (GB)
- Lovisenberg Diakonale Høgskole (NO)
- Medical Research Council (GB)
Publication Details
- Journal
- BMC Medicine
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1186/s12916-026-04692-4
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00