Two-Week Interval Hypofractionated Stereotactic Radiosurgery for Benign Intracranial Tumors: Volumetric Kinetics and Radiobiological Rationale
Hypofractionated stereotactic radiosurgery delivered at fixed two-week intervals achieved excellent tumor control with acceptable toxicity in selected benign intracranial tumors. These findings support the clinical feasibility of a fixed two-week inter-fraction interval and suggest that fraction timing may represent a biologically relevant treatment parameter influencing early volumetric response patterns without compromising long-term outcomes.
Authors
- Seung Woo Hong (ORCID: https://orcid.org/0000-0003-3021-5216)
- Junhyung Kim (ORCID: https://orcid.org/0000-0002-8908-978X)
- Won Hee Lee (ORCID: https://orcid.org/0000-0002-3112-5354)
- Won Seok Chang
- Jong Hee Chang
- Jinu Rim
- Jung Woo Yu
- Hyun Ho Jung
Institutions
- Inje University Busan Paik Hospital (KR)
- Hanyang University Seoul Hospital (KR)
- Gangnam Severance Hospital (KR)
Publication Details
- Journal
- Cancers
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3390/cancers18040617
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea