Epidemiology, clinical treatment and outcomes, susceptibility patterns and genotypic analysis of 214 Nocardia strains from multiple centers in Henan Province
This study provides a comprehensive evaluation of the epidemiology, phenotypic and genotypic profiles, and clinical treatment of <i>Nocardia</i> species in Henan, China. TMP-SMX and LZD can be used respectively for the clinical routine and critical treatment of nocardiosis. Particular emphasis is placed on the fact that antibiotic resistance and pathogenicity are species - specific, therefore, the AST of <i>Nocardia</i> isolates should be conducted and standardized, and attempts should be made to monitor its resistance molecular mechanisms.
Authors
- Xiaogai Li (ORCID: https://orcid.org/0000-0001-8522-4705)
- Wanhai Wang (ORCID: https://orcid.org/0000-0001-5354-5627)
- Cailin Liu
- Xiuping Lei
- G. Li (ORCID: https://orcid.org/0009-0005-4924-2195)
- Hui Xu (ORCID: https://orcid.org/0000-0003-3424-1219)
- Limin Guo
- Juhua Chen
- Xiangyang Chen
- Haijun Li
- Yinyin Hu
- Nan Zhang
- Yujuan Meng
Institutions
- Second Affiliated Hospital of Zhengzhou University (CN)
- Fifth Affiliated Hospital of Zhengzhou University (CN)
- Nanyang Institute of Technology (CN)
- Fuyang Maternity and Child Health Care Hospital (CN)
- Luoyang Central Hospital Affiliated to Zhengzhou University (CN)
- Xinxiang Central Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Xiangyang Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fcimb.2026.1728269
- Primary Topic
- Actinomycetales infections and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Zhengzhou University
- First Affiliated Hospital of Zhengzhou University