Real-world comparative effectiveness of FOLFIRINOX versus gemcitabine/nab-paclitaxel in metastatic pancreatic cancer: prognostic impact of metastatic site and burden in a Middle Eastern cohort
In this real-world Middle Eastern group, survival outcomes were comparable between FEX and GnP. The metastatic site, particularly lung involvement, emerged as a critical prognostic predictor, implying biological heterogeneity among metastatic PC subtypes and underlining the importance of metastatic pattern in clinical prognosis.
Authors
- Shamel Soaida
- Ramy Abbas
- Fawzy Elbarbry (ORCID: https://orcid.org/0000-0002-5238-2712)
- Wesal M. Eldehna
- Rafat I. Abu Shakra
- Wael M. Wagdy
- Abrar Aljohani
- Zeinab A. Morsi
- Shaimaa A. Elrasad
Institutions
- Pacific University Oregon (US)
- Cairo University (EG)
- Taif University (SA)
- South Valley University (EG)
- Mansoura University Hospital (EG)
- King Abdullah International Medical Research Center (SA)
- King Fahad Hospital Jeddah (SA)
Publication Details
- Journal
- Journal of Gastrointestinal Oncology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.21037/jgo-2025-aw-913
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kafrelsheikh University