Dynamic FIB-4 trajectory and a multi-state Markov model analysis reveal fibrosis progression and cardiovascular-cerebrovascular risk in MAFLD patients
Monitoring FIB-4 trajectory aids in the early identification and intervention of high-risk MAFLD patients, potentially preventing irreversible fibrosis and reducing CCEs risk.
Authors
- Jiaming Liang (ORCID: https://orcid.org/0000-0001-7273-495X)
- Yahong Chen
- Si-yan Yan
- Shao-wei Li
- Ling-ling Yan
- Xin-li Mao
- Shi-wen Xu
- Xin-yu Fu
- Ya-fei Ye
- Shan-jing Xu
- Ya-qi Song
- Jia-li Ma
Institutions
- Dalian Medical University (CN)
- Wenzhou Medical University (CN)
- First Hospital of Jiaxing (CN)
- Zhejiang Taizhou Hospital (CN)
Publication Details
- Journal
- Nutrition Metabolism and Cardiovascular Diseases
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.numecd.2026.104617
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 31.52
Funders
- Medical Science and Technology Project of Zhejiang Province
- Science and Technology Program of Zhejiang Province