When Myxoma Meets Bicuspid Aortic Valve: A Rare and Unexpected Cardiac Association

Atrial myxoma is the most common primary cardiac tumor in adults. It is generally sporadic, although an embryological origin has been suggested, as tumor cells are thought to arise from mesodermal embryonic remnants trapped within the interatrial septum. Bicuspid Aortic Valve (BAV), on the other hand, represents the most common congenital valvular anomaly. The simultaneous association of these two entities is exceptional and rarely reported in the literature. We report the case of an adult patient without any known genetic syndrome in whom this coexistence was identified. This case raises etiological, diagnostic and therapeutic questions and highlights the importance of a comprehensive cardiovascular evaluation when multiple cardiac abnormalities are present.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-02-19
DOI
https://doi.org/10.5281/zenodo.18627393
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
0.00
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article

When Myxoma Meets Bicuspid Aortic Valve: A Rare and Unexpected Cardiac Association

LACHHAB FADOUA, Fagouri Rime, Moughil Said, Kacemi Amal Drissi
Zenodo (CERN European Organization for Nuclear Research)
Cardiac tumors and thrombi
article

When Myxoma Meets Bicuspid Aortic Valve: A Rare and Unexpected Cardiac Association

LACHHAB FADOUA, Fagouri Rime, Moughil Said, Kacemi Amal Drissi
article en

Abstract

Atrial myxoma is the most common primary cardiac tumor in adults. It is generally sporadic, although an embryological origin has been suggested, as tumor cells are thought to arise from mesodermal embryonic remnants trapped within the interatrial septum. Bicuspid Aortic Valve (BAV), on the other hand, represents the most common congenital valvular anomaly. The simultaneous association of these two entities is exceptional and rarely reported in the literature. We report the case of an adult patient without any known genetic syndrome in whom this coexistence was identified. This case raises etiological, diagnostic and therapeutic questions and highlights the importance of a comprehensive cardiovascular evaluation when multiple cardiac abnormalities are present.

Zenodo (CERN European Organization for Nuclear Research)
Mohammed V University (MA)
Good health and well-being
Openalex Percentile: Top 59%
Cardiac tumors and thrombi
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