The role of soluble toll-like receptor-2 and 4 in children with pneumonia: a combined analysis of saliva and serum samples
This study demonstrates that salivary TNF-α, soluble TLR-2 and TLR-4 may serve as promising non-invasive biomarkers for diagnosing and stratifying pediatric pneumonia.
Authors
- Sevilay Karahan (ORCID: https://orcid.org/0000-0002-8692-7266)
- Ozlem Necipoglu (ORCID: https://orcid.org/0000-0002-6426-2857)
- Yasemin Özsürekçi (ORCID: https://orcid.org/0000-0001-8662-6909)
- Malik Aydin (ORCID: https://orcid.org/0000-0001-5684-2416)
- Kübra Aykaç (ORCID: https://orcid.org/0000-0002-0974-4765)
- Ali Bülent Cengiz (ORCID: https://orcid.org/0000-0002-2628-6954)
- Osman Oguz Demir
Institutions
- Witten/Herdecke University (DE)
- Hospital for Sick Children (CA)
- Hacettepe University (TR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fimmu.2026.1657027
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hacettepe Üniversitesi