Spatial transcriptomics reveals the mechanistic role of lactate metabolism in the pancreatic ductal adenocarcinoma microenvironment
This study provides insights into PDAC metabolic features and highlights lactate metabolism as a potential therapeutic target. The identified biomarkers could facilitate early diagnosis and improve treatment strategies, ultimately enhancing patient outcomes.
Authors
- Luting Zhang
- Zhe Tang (ORCID: https://orcid.org/0009-0005-9849-5105)
- Jie Lian (ORCID: https://orcid.org/0000-0002-7237-7347)
- Fan Gao
Institutions
- Shaoxing No.6 People's Hospital (CN)
- Shaoxing People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fimmu.2026.1743187
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00