Assessing measles immunity in individuals of childbearing age in Toronto, Ontario, Canada
Nearly one-fifth of mothers in our study were seronegative to measles, increasing to nearly one-third of mothers under 30 years. The higher susceptibility observed in younger individuals within a highly-vaccinated cohort may suggest waning humoral immunity. Further research is needed to understand the significance of the high proportion of seronegative individuals in younger age groups.
Authors
- Susan E. Richardson (ORCID: https://orcid.org/0000-0002-7751-7628)
- Callum Arnold (ORCID: https://orcid.org/0000-0002-3245-6956)
- Elizabeth McLachlan
- Dara Petel (ORCID: https://orcid.org/0009-0002-2067-0223)
- Shelly Bolotin (ORCID: https://orcid.org/0000-0002-9100-5928)
- Selma Osman (ORCID: https://orcid.org/0000-0003-3642-4932)
- Todd Hatchette
- Shelley L. Deeks
- Natasha Crowcroft
- Alberto Severini
- James Wright
- Kevin Brown
- Michelle Science
- Scott A Halperin
Institutions
- Dalhousie University (CA)
- Public Health Agency of Canada (CA)
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- Canada Research Chairs (CA)
- Public Health Ontario (CA)
- SickKids Foundation (CA)
Publication Details
- Journal
- Journal of Infection
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1016/j.jinf.2026.106701
- Primary Topic
- Virology and Viral Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Institutes of Health Research