Construction and validation of a novel diagnostic model for esophageal squamous cell carcinoma: an integrated analysis of multi-omics data
We developed an ESCC diagnostic model and identified <i>BID</i>, <i>CBX3</i>, <i>ECT2</i>, <i>KIF14</i>, and <i>SORBS2</i> as robust ESCC biomarkers. <i>SORBS2</i> is a tumor-suppressor gene predominantly expressed in myofibroblasts.
Authors
- Nuo Li (ORCID: https://orcid.org/0000-0003-1106-8783)
- Yijing Yan
- Chenxin Zhu
- Zhibin Wu
- Shengjuan Hu (ORCID: https://orcid.org/0000-0002-1007-5562)
- Yue Jin
- Yiyuan Cui
- Yufan Chen
- Xinyu Li
- Jingjie Yu
- Li Feng
- Jiayang Chen
- Sicong Li (ORCID: https://orcid.org/0000-0002-6414-6645)
- Jinyuan Chang
Institutions
- National Cancer Center (US)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.3389/fimmu.2026.1685902
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00