The association of C-reactive protein–triglyceride–glucose index with cardiometabolic multimorbidity in middle-aged and older adults: evidence from two cohort studies

CTI and its cumulative exposure level are closely associated with both the prevalence and incidence risk of CMM, and these findings were further supported by validation in the independent longitudinal ELSA cohort. As a simple composite index derived from routinely measured indicators, CTI may help identify individuals at high risk of CMM and provide a reference for early risk stratification and intervention in middle-aged and older populations.