Next Generation Sequencing of Tracheal Aspirates in Children With Tracheostomy A Prospective Case‐Control Study
NGS can effectively identify a wide spectrum of DNA-based pathogens (bacteria, viruses, and fungi) in the tracheal aspirates of children. Tracheostomized children were significantly more likely to be colonized by difficult-to-treat bacteria. Future research is required to evaluate the clinical benefits of NGS compared with standard microbiological procedures.
Authors
- Sonia Mazzitelli
- Michael Hilder
- Silke Grumaz
- Pia Brensing (ORCID: https://orcid.org/0009-0005-7965-8888)
- Julia Lutynski
Institutions
- Entwicklungszentrum für Schiffstechnik und Transportsysteme (DE)
- Essen University Hospital (DE)
- University of Duisburg-Essen (DE)
Publication Details
- Journal
- Pediatric Pulmonology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/ppul.71511
- Primary Topic
- Tracheal and airway disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00