Pseudopodia lentis and preretinal deposit in systemic amyloidosis

Fig. 1 The clinical characters of ocular involvement of amyloidosis.A External slit-lamp photography demonstrates whitish amyloid deposits adherent to the posterior lens capsule, forming the characteristic pseudopodia lentis appearance (white arrowhead).B Ultrawide-field fundus imaging shows central vitreous opacities with marked obscuration of underlying retinal details.C Following diagnostic and therapeutic pars plana vitrectomy of the left eye, postoperative optical coherence tomography (OCT) shows multiple needle-shaped preretinal hyperreflective deposits (white arrowhead), indicating that even after surgical posterior vitreous detachment, amyloid can continue to accumulate on the retinal surface.Collectively, these multimodal imaging features are characteristic of vitreous amyloidosis associated with familial amyloid polyneuropathy (FAP) and assist in differentiating this condition from other causes of vitreous opacity.