DBS-related infections in Parkinson's disease: Incidence, risk factors, management and outcome

We found low incidence of DBS-related infections following primary DBS implantation or IPG replacement in PD patients, depending on PD duration. Our study highlights that patient-specific and multidisciplinary management in expert center resulted in good outcome and high rates of reimplantation following primary implantation-related infection, whereas PD patients with IPG replacement-associated infection had more severe outcome and challenging management.

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Publication Details

Journal
Revue Neurologique
Published
2026-02-01
DOI
https://doi.org/10.1016/j.neurol.2026.01.006
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

DBS-related infections in Parkinson's disease: Incidence, risk factors, management and outcome

G. Polo, T. Ferry, E. Metereau, C. Laurencin et al.
Revue Neurologique
Parkinson's Disease Mechanisms and Treatments
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DBS-related infections in Parkinson's disease: Incidence, risk factors, management and outcome

G. Polo, T. Ferry, E. Metereau, C. Laurencin, M. Bonjour, M. Duraffourg, T. Danaila, S. Thobois, S. Prange, F. Valour, L. C. Liu, A. Jaulent, E. Simon, P. Jaulent, M. Desnoyers
article en

Abstract

We found low incidence of DBS-related infections following primary DBS implantation or IPG replacement in PD patients, depending on PD duration. Our study highlights that patient-specific and multidisciplinary management in expert center resulted in good outcome and high rates of reimplantation following primary implantation-related infection, whereas PD patients with IPG replacement-associated infection had more severe outcome and challenging management.

Revue Neurologique
Université Claude Bernard Lyon 1 (FR), École Normale Supérieure de Lyon (FR), Centre National de la Recherche Scientifique (FR), Inserm (FR), Centre de Recherche en Neurosciences de Lyon (FR), Hôpital Pierre Wertheimer (FR), Laboratoire de Biométrie et Biologie Evolutive (FR)
Good health and well-being
Openalex Percentile: Top 60%
Parkinson's Disease Mechanisms and Treatments
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