Peri-Implantitis—An Overview of Treatment Options and a New Approach to the Treatment of Peri-Implantitis Using a Magnesium Membrane in Three Case Reports

<b>Background/Objectives:</b> Dental implants are a preferred solution for missing teeth, but peri-implantitis remains a major challenge in implant dentistry. This narrative review provides an overview of the therapeutic interventions for peri-implantitis based on the current literature and illustrates a new clinical approach using novel magnesium membrane through three case presentations. <b>Methods:</b> A comprehensive literature search on peri-implantitis management was conducted, with emphasis on current clinical practice guidelines. In addition, three clinical cases were presented to demonstrate the use of a fully resorbable magnesium membrane in combination with a bovine xenograft with hyaluronate. <b>Results:</b> The narrative review identified and summarized a wide range of non-surgical and surgical therapeutic strategies for treatment of peri-implantitis. Additionally, three case reports with novel magnesium membrane highlighted distinct clinical scenarios: (1) bone defect reconstruction without implant removal, (2) reconstruction following implant removal, and (3) a minimally invasive shield technique performed without removal of the implant or crown. All cases demonstrated favorable clinical outcomes following the novel biomaterial approach. <b>Conclusions:</b> The combination of a resorbable magnesium membrane with bovine xenograft with hyaluronate represents a promising therapeutic strategy for treatment of peri-implantitis. This approach may improve clinical outcomes and potentially set new standards in implant dentistry. Further studies with larger cohorts and control groups are required to confirm these preliminary findings.