Disability and Relapse Risk in Late-Onset Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease

In this cohort study of MOGAD, late onset was not associated with a risk of relapse but with a higher risk of moderate disability at follow-up. Prospective studies with longer follow-up periods are warranted to better understand and manage patients with late-onset disease.

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Publication Details

Journal
JAMA Network Open
Published
2026-02-13
DOI
https://doi.org/10.1001/jamanetworkopen.2025.59471
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Disability and Relapse Risk in Late-Onset Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease

Woojun Kim, Eunhee Sohn, Sun-Young Oh, Jeeyoung Oh et al.
JAMA Network Open
Multiple Sclerosis Research Studies
article

Disability and Relapse Risk in Late-Onset Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease

Woojun Kim, Eunhee Sohn, Sun-Young Oh, Jeeyoung Oh, Jae‐Joong Kim, Jeong Bin Bong, Sooyoung Kim, Yeon Hak Chung, In Soo Joo, Eun‐Jae Lee, Sook Young Woo, Jin‐Woo Park, Jiwon Yang, Min Su Park, Byung-jo Kim, Woohee Ju, Hyunjin Ju, You-Ri Kang, Seong-il Oh, Young-Min Lim, Byeol-A Yoon, Sukyoon Lee, Jong Kuk Kim, Ju-Hong Min, S W Kwon, Hyung-Soo Lee, Su-Hyun Kim, Ha Young Shin, Wookyung Kim, Nam-Hee Kim, Suk-Won Ahn, Young Nam Kwon, Hyunjin Kim, Ho Jin Kim, Sung-Min Kim, Seung Woo Kim, Ki Hoon Kim, Hung Youl Seok, Tae-Kyeong Lee, Sohyeon Kim
article en

Abstract

In this cohort study of MOGAD, late onset was not associated with a risk of relapse but with a higher risk of moderate disability at follow-up. Prospective studies with longer follow-up periods are warranted to better understand and manage patients with late-onset disease.

JAMA Network OpenVol. 9(2)
Ulsan College (KR), Gachon University (KR), Ewha Womans University (KR), Hallym University (KR), Chosun University (KR), Yonsei University (KR), Korea University (KR), Samsung (South Korea) (KR), Soonchunhyang University (KR), Severance Hospital (KR), Korea University Medical Center (KR), Soonchunhyang University Hospital Seoul (KR), Asan Medical Center (KR), Samsung Medical Center (KR), Seoul National University Hospital (KR), Kyungpook National University (KR), Kyung Hee University (KR), University of Ulsan (KR), Konkuk University Medical Center (KR), Chonnam National University Hospital (KR), Dongguk University Ilsan Hospital (KR), Inje University Busan Paik Hospital (KR), National Cancer Center (KR), Chungnam National University Hospital (KR), Kangdong Sacred Heart Hospital (KR), National Medical Center (KR), Inha University Hospital (KR), Chung-Ang University Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Dong-A University (KR), Keimyung University (KR), Ajou University (KR), Bucheon University (KR), Jeonbuk National University (KR), Sungkyunkwan University (KR), Catholic University of Korea (KR), Daegu University (KR)
Openalex Percentile: Top 58%
Multiple Sclerosis Research Studies
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