EC50 of Remifentanil for Inhibiting Cardiovascular Responses to Tracheal Intubation in Patients Treated by Different Doses of Oliceridine: A Randomized Controlled Trial Using Up-and-Down Sequential Allocation Methodology

The effect of 0.03 mg/kg oliceridine is similar to 0.15 μg/kg sufentanil in reducing the EC<sub>50</sub> of remifentanil in inhibiting the cardiovascular responses induced by trachea intubation.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2026-02-01
DOI
https://doi.org/10.2147/dddt.s571007
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
0.00

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article

EC50 of Remifentanil for Inhibiting Cardiovascular Responses to Tracheal Intubation in Patients Treated by Different Doses of Oliceridine: A Randomized Controlled Trial Using Up-and-Down Sequential Allocation Methodology

Xiaolin Wang, Yaqin Xiao, Lingling Ge, Zhenzhen Zhao et al.
Drug Design Development and Therapy
Anesthesia and Sedative Agents
article

EC50 of Remifentanil for Inhibiting Cardiovascular Responses to Tracheal Intubation in Patients Treated by Different Doses of Oliceridine: A Randomized Controlled Trial Using Up-and-Down Sequential Allocation Methodology

Xiaolin Wang, Yaqin Xiao, Lingling Ge, Zhenzhen Zhao, Jia-Feng Wang, Yan Zhou, Rui Bao, Ying Zhang, Xiandong Wang, Jie Huang
article en

Abstract

The effect of 0.03 mg/kg oliceridine is similar to 0.15 μg/kg sufentanil in reducing the EC<sub>50</sub> of remifentanil in inhibiting the cardiovascular responses induced by trachea intubation.

Drug Design Development and TherapyVol. Volume 20
Second Military Medical University (CN), Changhai Hospital (CN)
National Natural Science Foundation of China, Changhai Hospital of Shanghai
Good health and well-being
Openalex Percentile: Top 56%
Anesthesia and Sedative Agents
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