Clinical, laboratory, and radiological features of community-acquired pneumonia due to <i>Chlamydia psittaci</i> and <i>Legionella pneumophila</i> confirmed using next-generation sequencing

LPP demonstrated greater initial clinical and laboratory severity compared to CPP. Under NGS-guided targeted therapy, both groups achieved comparable outcomes. The observational finding that both pathogens respond to azithromycin and cause severe disease when left undetected underscore the value of guideline-recommended β-lactams/macrolide combination therapy in CAP settings, particularly where these intracellular pathogens remain undiagnosed without NGS.