“Efficacy and safety of bimekizumab in moderate-to-severe hidradenitis suppurativa: A systematic review and meta-analysis of RCTs”

The evidence, although derived from a limited number of trials, demonstrates the superiority of bimekizumab over placebo. For patients with moderate-to-severe HS, bimekizumab showed significantly improved outcomes compared to placebo in terms of enhancing clinical response and lessening skin pain. Although no statistically significant increase in serious adverse events was observed, a potential risk cannot be definitively ruled out given the numerical imbalance.

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Publication Details

Journal
Medicine
Published
2026-02-13
DOI
https://doi.org/10.1097/md.0000000000047691
Primary Topic
Hidradenitis Suppurativa and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

“Efficacy and safety of bimekizumab in moderate-to-severe hidradenitis suppurativa: A systematic review and meta-analysis of RCTs”

Osama A Mobarki, Abdullah Alghamdi, Muhammad A Almahdi, Wesam Alharbi et al.
Medicine
Hidradenitis Suppurativa and Treatments
article

“Efficacy and safety of bimekizumab in moderate-to-severe hidradenitis suppurativa: A systematic review and meta-analysis of RCTs”

Osama A Mobarki, Abdullah Alghamdi, Muhammad A Almahdi, Wesam Alharbi, Rimas A. Sumayli, Mohammed Alturkistani, Suhayb Alhazmi, Ahmad Assiri, Nawaf Alharbi
article en

Abstract

The evidence, although derived from a limited number of trials, demonstrates the superiority of bimekizumab over placebo. For patients with moderate-to-severe HS, bimekizumab showed significantly improved outcomes compared to placebo in terms of enhancing clinical response and lessening skin pain. Although no statistically significant increase in serious adverse events was observed, a potential risk cannot be definitively ruled out given the numerical imbalance.

MedicineVol. 105(7)
Umm al-Qura University (SA), Jazan University (SA)
Good health and well-being
Openalex Percentile: Top 56%
Hidradenitis Suppurativa and Treatments
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