LDL-C target achievement after adding evinacumab in 2 patients with autosomal recessive hypercholesterolemia

These cases demonstrate a marked and clinically meaningful LDL-C-lowering effect of evinacumab in ARH, supporting its use as an effective LDL-R-independent therapeutic option.

Authors

Giuliana Mombelli (ORCID: https://orcid.org/0000-0003-2886-134X)
Francesco Vicari
Antonia Alberti
Cesare Riccardo Sirtori
Chiara Moschetti
Laura Calabresi

Institutions

AOL (United States) (US)
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)

Publication Details

Journal: Journal of clinical lipidology
Published: 2026-02-01
DOI: https://doi.org/10.1016/j.jacl.2026.02.007
Primary Topic: Lipoproteins and Cardiovascular Health
Type: article
Field-Weighted Citation Impact: 0.00

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article

LDL-C target achievement after adding evinacumab in 2 patients with autosomal recessive hypercholesterolemia

Giuliana Mombelli, Francesco Vicari, Antonia Alberti, Cesare Riccardo Sirtori et al.

Feb 1, 2026

Journal of clinical lipidology

Lipoproteins and Cardiovascular Health

article

LDL-C target achievement after adding evinacumab in 2 patients with autosomal recessive hypercholesterolemia

Giuliana Mombelli, Francesco Vicari, Antonia Alberti, Cesare Riccardo Sirtori, Chiara Moschetti, Laura Calabresi

February 1, 2026article en

Abstract

These cases demonstrate a marked and clinically meaningful LDL-C-lowering effect of evinacumab in ARH, supporting its use as an effective LDL-R-independent therapeutic option.

Journal of clinical lipidology

AOL (United States) (US), Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)

Zero hunger

Openalex Percentile: Top 58%

Lipoproteins and Cardiovascular Health

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LDL-C target achievement after adding evinacumab in 2 patients with autosomal recessive hypercholesterolemia — Giuliana Mombelli, Francesco Vicari, et al. · Journal of clinical lipidology (2026) | TGRS Research Map | TGRS