Optical coherence tomography and elastography for ex vivo visualization of early gastric cancer
This proof-of-concept study provides evidence that OCT and OCE may be capable of visualizing differences in tissue structure and stiffness between normal, metaplastic, dysplastic, and early cancerous gastric tissue, potentially providing the basis for improved screening tools with higher sensitivity.
Authors
- Alana Gonzales (ORCID: https://orcid.org/0000-0003-1035-5465)
- Jennifer K. Barton (ORCID: https://orcid.org/0000-0003-4897-9361)
- Stephen Mead
- Sarah E. Bohndiek (ORCID: https://orcid.org/0000-0003-0371-8635)
- Ashraf Sanduka
- Graham Spicer (ORCID: https://orcid.org/0000-0002-8360-463X)
- Travis W. Sawyer (ORCID: https://orcid.org/0000-0002-6911-0289)
- Massimiliano di Pietro (ORCID: https://orcid.org/0000-0003-4866-7026)
- Amy M. Winkler
- Caitlin Ruhland
- Ryan H. W. Mitstifer
Institutions
- University of Arizona (US)
- University of Cambridge (GB)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1117/1.jbo.31.2.026501
- Primary Topic
- Optical Coherence Tomography Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- UK Research and Innovation
- Cancer Research UK
- Engineering and Physical Sciences Research Council