B-cell maturation antigen-Targeted T-cell Engager Therapy Combined with B-cell Depletion for Treatment of Refractory HLA Sensitization
This dual-agent immunotherapeutic strategy achieved unprecedented depletion of high-titer, preformed anti-HLA antibodies and represents a promising approach for patients with prohibitive sensitization.
Authors
- Tifanie Blein (ORCID: https://orcid.org/0000-0002-3416-3786)
- Antoine Troger
- Stéphanie Chhun (ORCID: https://orcid.org/0000-0001-6278-4128)
- Jacques Fourgeaud (ORCID: https://orcid.org/0000-0003-3631-184X)
- Simon Fillatreau (ORCID: https://orcid.org/0000-0002-7730-9917)
- Cédric Usureau (ORCID: https://orcid.org/0009-0002-4366-7211)
- Camille Cotteret
- Camille Gons
- Magali Devriese (ORCID: https://orcid.org/0000-0003-1198-4677)
- Marc‐Olivier Timsit
- Florence Alameda
- Jean‐Luc Taupin
- Thu Ngân Nguyễn
- Marion Rabant
- Camille Roger
- Julien Zuber
- Marie-Bénédicte Le Stang
- Marie Roelens
- Felipe Suarez
- Juliette Leon
- Carole Burger
- Dany Anglicheau
- Olivier Aubert
- Soëli Charbonnier
- Alexis Talbot
Institutions
- Hôpital Necker-Enfants Malades (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Institut Necker Enfants Malades (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Hôpital Européen (FR)
- Hôpital Saint-Louis (FR)
Publication Details
- Journal
- Kidney International
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.kint.2026.01.020
- Citations
- 1
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 24.20