Vaccines against chronic <i>Trypanosoma cruzi</i> infection: progress, challenges and future directions

Pre-clinical studies broadly support the clinical development of a Chagas disease vaccine, particularly for a therapeutic vaccine. Synergy with drug development efforts, which face many of the same challenges, may provide new opportunities to strengthen clinical development and trials of drugs, vaccines and combined therapies.

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Publication Details

Journal
Expert Review of Vaccines
Published
2026-02-13
DOI
https://doi.org/10.1080/14760584.2026.2632658
Primary Topic
Trypanosoma species research and implications
Type
article
Field-Weighted Citation Impact
0.00
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article

Vaccines against chronic Trypanosoma cruzi infection: progress, challenges and future directions

Claudia Herrera, Eric Dumonteil
Expert Review of Vaccines
Trypanosoma species research and implications
article

Vaccines against chronic Trypanosoma cruzi infection: progress, challenges and future directions

Claudia Herrera, Eric Dumonteil
article en

Abstract

Pre-clinical studies broadly support the clinical development of a Chagas disease vaccine, particularly for a therapeutic vaccine. Synergy with drug development efforts, which face many of the same challenges, may provide new opportunities to strengthen clinical development and trials of drugs, vaccines and combined therapies.

Expert Review of VaccinesVol. 25(1)
Tulane University (US)
Good health and well-being
Openalex Percentile: Top 56%
Trypanosoma species research and implications
DOIOpen Access PDFOpenAlex
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Vaccines against chronic <i>Trypanosoma cruzi</i> infection: progress, challenges and future directions — Claudia Herrera, Eric Dumonteil · Expert Review of Vaccines (2026) | TGRS Research Map | TGRS