Proteome-wide analysis by liquid chromatography tandem mass spectrometry reveals the role of retinoic acid during adipogenesis in human bone mesenchymal stem cells
Our study suggests that ATRA downregulates metabolism-related pathways to inhibit the adipogenesis of hBMSCs by upregulating some classic signaling pathways and cytoskeleton-related pathways, indicating that ATRA may be a broad-spectrum metabolic inhibitor.
Authors
- Jun Cao (ORCID: https://orcid.org/0000-0002-3899-4878)
- Y. S. Chen (ORCID: https://orcid.org/0000-0002-0270-7953)
- Shilei Nong
- Siyu Chen (ORCID: https://orcid.org/0000-0002-9438-8776)
- Zhenjie Wang
- Jiaxin Peng
- Tao Wang
Institutions
- Jiujiang University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-02-13
- DOI
- https://doi.org/10.7717/peerj.20846
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00