Mechanisms of therapy resistance in the tumor microenvironment: Insights from antibody array–based cytokine profiling
Cytokine-driven signaling within the TME plays a central role in therapy resistance. Protein profiling studies have contributed mechanistic insight into these interactions and helped define resistance-associated pathways across treatment settings. Ongoing clinical studies will determine how targeting these pathways can be most effectively applied to improve patient outcomes.
Authors
- Shuhong Luo (ORCID: https://orcid.org/0000-0003-3058-8899)
- Guogui Sun
- Rochelle N. Wickramasekara (ORCID: https://orcid.org/0000-0003-3090-9357)
- Valerie Jones
- Yating Zhao
- Ruo-Pan Huang
Institutions
- North China University of Science and Technology (CN)
- Biocure (United States) (US)
- North China University of Science and Technology Affiliated Hospital (CN)
- RayBiotech (China) (CN)
Publication Details
- Journal
- Drug Resistance Updates
- Published
- 2026-02-14
- DOI
- https://doi.org/10.1016/j.drup.2026.101378
- Primary Topic
- Advanced Biosensing Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00