The APOBEC3 family: a narrative review of an alternative therapeutic agent for hepatitis B virus-induced hepatocellular carcinoma
The paradoxical nature of the A3 protein family-possessing both antiviral properties and carcinogenic potential-highlights its complex role in HBV-HCC. Understanding these regulatory mechanisms may provide novel insights into developing innovative management strategies for HBV-HCC.
Authors
- Lantian Huang
- En Ren (ORCID: https://orcid.org/0000-0002-4976-5050)
- Kaifeng He
- Jing Miao
- Zhi-Gang Gao
- Meng Zhang
Institutions
- Children's Hospital of Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of Gastrointestinal Oncology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.21037/jgo-2025-1-1073
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Zhejiang University
- Natural Science Foundation of Zhejiang Province