Safety and efficacy of tranexamic acid and beta-blockers for traumatic brain injury: A systematical review and meta-analysis

TXA and BB are safe but do not significantly improve mortality in TBI. Our updated analysis aligns with recent literature, underscoring the need for further RCTs to clarify subgroups (e.g., mild-moderate TBI) that may benefit.

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Publication Details

Journal
Surgical Neurology International
Published
2026-02-13
DOI
https://doi.org/10.25259/sni_598_2025
Primary Topic
Blood transfusion and management
Type
article
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article

Safety and efficacy of tranexamic acid and beta-blockers for traumatic brain injury: A systematical review and meta-analysis

Aditya Wicaksana, Rita Trisnawati Sugianto, Ahmad Faried, I. Nengah Kuning Atmadjaya et al.
Surgical Neurology International
Blood transfusion and management
article

Safety and efficacy of tranexamic acid and beta-blockers for traumatic brain injury: A systematical review and meta-analysis

Aditya Wicaksana, Rita Trisnawati Sugianto, Ahmad Faried, I. Nengah Kuning Atmadjaya, Rivan Dwiutomo
article en

Abstract

TXA and BB are safe but do not significantly improve mortality in TBI. Our updated analysis aligns with recent literature, underscoring the need for further RCTs to clarify subgroups (e.g., mild-moderate TBI) that may benefit.

Surgical Neurology InternationalVol. 17
Kappa Omicron Nu Honor Society (US), Padjadjaran University (ID)
Good health and well-being
Openalex Percentile: Top 58%
Blood transfusion and management
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