A chemiluminescent microfluidic thrombin generation assay for real-time monitoring in patient plasma

This study provides proof-of-concept that the present microfluidic TGA<sub>lum</sub> is applicable for monitoring therapy of pwHA at a global level and monitoring anticoagulant therapy with DOACs using a portable readout device.

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Publication Details

Journal
Journal of Thrombosis and Haemostasis
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jtha.2026.01.021
Primary Topic
Hemophilia Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

A chemiluminescent microfluidic thrombin generation assay for real-time monitoring in patient plasma

Mark van Geffen, Waander L. van Heerde, Lisa van Engelshoven, Saskia E.M. Schols et al.
Journal of Thrombosis and Haemostasis
Hemophilia Treatment and Research
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A chemiluminescent microfluidic thrombin generation assay for real-time monitoring in patient plasma

Mark van Geffen, Waander L. van Heerde, Lisa van Engelshoven, Saskia E.M. Schols, Theodora J. Steeghs, Henriëtte W. Huijzer, Nicole M.A. Blijlevens, Cornelis van ’t Veer, Claudia J. van de Ridder, Nerissa M.M. Coolen
article en

Abstract

This study provides proof-of-concept that the present microfluidic TGA<sub>lum</sub> is applicable for monitoring therapy of pwHA at a global level and monitoring anticoagulant therapy with DOACs using a portable readout device.

Journal of Thrombosis and Haemostasis
Radboud University Nijmegen (NL), Radboud University Medical Center (NL)
Openalex Percentile: Top 56%
Hemophilia Treatment and Research
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