Chronotype and sleep duration in relation to leukaemia subtypes: a two-sample Mendelian randomization analysis

Our MR study found several nominal associations that sleep traits causally influence leukaemia subtypes. Nominal associations were not significant after multiple testing correction, attenuated by adjustment for smoking and BMI, and potentially affected by pleiotropy or reverse causation.

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Publication Details

Journal
Hematology
Published
2026-02-13
DOI
https://doi.org/10.1080/16078454.2026.2626211
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00
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article

Chronotype and sleep duration in relation to leukaemia subtypes: a two-sample Mendelian randomization analysis

Jiang Liu, Jinlv Liu, Ruijuan Zhang, Ling Zhang et al.
Hematology
Circadian rhythm and melatonin
article

Chronotype and sleep duration in relation to leukaemia subtypes: a two-sample Mendelian randomization analysis

Jiang Liu, Jinlv Liu, Ruijuan Zhang, Ling Zhang, Lina Wang
article en

Abstract

Our MR study found several nominal associations that sleep traits causally influence leukaemia subtypes. Nominal associations were not significant after multiple testing correction, attenuated by adjustment for smoking and BMI, and potentially affected by pleiotropy or reverse causation.

HematologyVol. 31(1)
Shanxi Medical University (CN), Shanxi Academy of Medical Sciences (CN)
Good health and well-being
Openalex Percentile: Top 54%
Circadian rhythm and melatonin
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