Colpocephaly in adulthood with neuropsychiatric presentation of status epilepticus and psychosis in emergency: A rare case report

Colpocephaly is a type of congenital ventriculomegaly characterized by enlarged occipital horns of the lateral ventricles. It is often associated with partial or complete agenesis of the corpus callosum. The diagnosis of colpocephaly is typically made in infancy. Its diagnosis in adulthood without associated clinical symptoms is infrequent and frequently confused with normal pressure hydrocephalus. However, it can be differentiated due to disproportionate posterior horn dilatation and early age of onset. We report a case of a 19-year-old female diagnosed incidentally with colpocephaly who presented to us with status epilepticus and psychotic symptoms. She improved on sodium valproate 750mg and olanzapine 10mg. To the best of our knowledge, this is the first case of colpocephaly in adulthood presenting with status epilepticus and psychosis.